4EBP1 Polyclonal antibody

4EBP1 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

ELISA and More (2)

Conjugate

Unconjugated

Cat No : 13988-1-AP

Print datasheet

Synonyms

4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I



经过测试的应用

推荐稀释比

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13988-1-AP targets 4EBP1 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications ELISA
Cited Applications IF, WB
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Immunogen 4EBP1 fusion protein Ag5056 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name eukaryotic translation initiation factor 4E binding protein 1
Synonyms 4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I
Calculated Molecular Weight 118 aa, 12 kDa
GenBank Accession NumberBC004459
Gene Symbol EIF4EBP1
Gene ID (NCBI) 1978
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13541
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Eukaryotic translation initiation factor 4E-binding protein 1(EIF4EBP1), is a member of 4E-BPs family, which regulate the translation of a subset of mRNAs by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation facotrs to form the complex and then initiates cap-dependent translation. It also mediates the regulation of protein translation by hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of EIF4EP1, alpha, beta and gamma.

发表文章

SpeciesApplicationTitle
humanIF

Cell Death Discov

The long non-coding RNA PVT1 promotes tumorigenesis of cutaneous squamous cell carcinoma via interaction with 4EBP1

Authors - Rong Li
mouseWB

J Ethnopharmacol

Iridoids from Gardeniae fructus ameliorates depression by enhancing synaptic plasticity via AMPA receptor-mTOR signaling

Authors - Baomei Xia