4EBP1 Polyclonal antibody
4EBP1 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA and More (2)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
推荐稀释比
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
WB | See 1 publications below |
IF | See 1 publications below |
产品信息
13988-1-AP targets 4EBP1 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | ELISA |
Cited Applications | IF, WB |
Tested Reactivity | human, mouse, rat |
Cited Reactivity | human, mouse |
Immunogen | 4EBP1 fusion protein Ag5056 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | eukaryotic translation initiation factor 4E binding protein 1 |
Synonyms | 4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I |
Calculated Molecular Weight | 118 aa, 12 kDa |
GenBank Accession Number | BC004459 |
Gene Symbol | EIF4EBP1 |
Gene ID (NCBI) | 1978 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q13541 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Eukaryotic translation initiation factor 4E-binding protein 1(EIF4EBP1), is a member of 4E-BPs family, which regulate the translation of a subset of mRNAs by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation facotrs to form the complex and then initiates cap-dependent translation. It also mediates the regulation of protein translation by hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of EIF4EP1, alpha, beta and gamma.
发表文章
Species | Application | Title |
---|---|---|
Cell Death Discov The long non-coding RNA PVT1 promotes tumorigenesis of cutaneous squamous cell carcinoma via interaction with 4EBP1 | ||
J Ethnopharmacol Iridoids from Gardeniae fructus ameliorates depression by enhancing synaptic plasticity via AMPA receptor-mTOR signaling |