- Featured Product
- KD/KO Validated
Inhibin Beta A Polyclonal antibody
Inhibin Beta A Polyclonal Antibody for IF/ICC, IHC, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (2)
Applications
IF/ICC, IHC, WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | HeLa cells, MCF-7 cells, A549 cells, SGC-7901 cells, BGC-823 cells, HepG2 cells |
| Positive IHC detected in | human lung cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF detected in | A549 cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| Immunofluorescence (IF) | IF : 1:20-1:200 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
10651-1-AP targets Inhibin Beta A in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
| Tested Applications | IF/ICC, IHC, WB, ELISA |
| Cited Applications | IF, IHC, WB |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse, sheep |
| Immunogen | Inhibin Beta A fusion protein Ag1001 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | inhibin, beta A |
| Synonyms | Activin beta A chain, EDF, FRP, INHBA, Inhibin Beta A, Inhibin beta A chain, Inhibin β-A, inhibin, beta A |
| Calculated Molecular Weight | 47 kDa |
| Observed Molecular Weight | 47 kDa |
| GenBank Accession Number | BC007858 |
| Gene Symbol | INHBA |
| Gene ID (NCBI) | 3624 |
| RRID | AB_2125851 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P08476 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Inhibin is a 32-kD dimeric glycoprotein consisting of an alpha subunit and one of two beta subunits (beta A or beta B) leading to inhibin A or B, respectively, which was isolated and cloned on the basis of its ability to inhibit FSH release from the pituitary. Inhibin beta A forms a disulfide-linked homo-dimer known as activin A, which has been implicated in multiple biologic processes, including neoplastic progression. The inhibin beta A can also bind the beta B and A isoforms to form activin AB and inhibin, respectively.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for Inhibin Beta A antibody 10651-1-AP | Download protocol |
| IHC protocol for Inhibin Beta A antibody 10651-1-AP | Download protocol |
| IF protocol for Inhibin Beta A antibody 10651-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Nat Commun Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation. | ||
Development Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination. | ||
PLoS One Action mechanism of inhibin α-subunit on the development of Sertoli cells and first wave of spermatogenesis in mice. | ||
Transl Oncol Multiregion single cell analysis reveals a novel subtype of cancer-associated fibroblasts located in the hypoxic tumor microenvironment in colorectal cancer | ||
BMC Cancer Esophageal squamous cell carcinoma invasion is inhibited by Activin A in ACVRIB-positive cells. |
