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  • KD/KO Validated

RAD51 Polyclonal antibody

RAD51 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, ELISA and More (2)

Conjugate

Unconjugated

Cat No : 14961-1-AP

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Synonyms

BRCC5, HRAD51, HsRad51, HsT16930, RAD51, RAD51 homolog A, RAD51A, RECA



经过测试的应用

Positive WB detected inHeLa cells, NIH/3T3 cells, mouse testis tissue, K-562 cells, MCF-7 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

14961-1-AP targets RAD51 in WB, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA
Cited Applications ChIP, CoIP, WB
Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, pig
Immunogen RAD51 fusion protein Ag6823 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Synonyms BRCC5, HRAD51, HsRad51, HsT16930, RAD51, RAD51 homolog A, RAD51A, RECA
Calculated Molecular Weight 37 kDa
Observed Molecular Weight 37 kDa
GenBank Accession NumberBC001459
Gene Symbol RAD51
Gene ID (NCBI) 5888
RRIDAB_2177083
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ06609
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

RAD51 plays a critical role in the maintenance of genomic integrity by functioning in the repair of DNA double-strand breaks. It mediates homologous pairing and strand exchange in recombinatory structures known as RAD51foci in the nucleus. It also can bind to single and double stranded DNA and exhibits DNA-dependent ATPase activity. In addition, it has a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.

实验方案

Product Specific Protocols
WB protocol for RAD51 antibody 14961-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouse

Nucleic Acids Res

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.

Authors - Yongjuan Guan
humanWB

Cell Death Differ

CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.

Authors - Yina Liao
humanWB

Nucleic Acids Res

LncRNA lnc-RI regulates homologous recombination repair of DNA double-strand breaks by stabilizing RAD51 mRNA as a competitive endogenous RNA.

Authors - Liping Shen
  • KD Validated
humanWB,CoIP

Cell Rep

C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair

Authors - Zenan Zhou
humanWB

Int J Biol Macromol

Antitumor efficacy of a recombinant EGFR-targeted fusion protein conjugate that induces telomere shortening and telomerase downregulation

Authors - Hong-Yu Tao
humanWB

Oncogene

BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.

Authors - Mengdong Ni