14-3-3 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14503-1-AP

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse, rat

Positive WB detected in:
NIH/3T3 cells, HeLa cells, human brain tissue, Jurkat cells, mouse brain tissue, mouse heart tissue, mouse kidney tissue, mouse liver tissue, mouse lung tissue, rat liver tissue

Positive IP detected in:
mouse lung tissue

Positive IHC detected in:
mouse brain tissue, human testis tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:6000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

Calculated molecular weight:
28 kDa

Observed molecular weight:
31 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
YWHAQ

Synonyms
14 3 3, 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 1C5, HS1, Protein HS1, YWHAQ
Background

14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.


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