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ABHD15 Polyclonal antibody

ABHD15 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 22526-1-AP

Print datasheet

Synonyms

ABHD15, Abhydrolase domain-containing protein 15, Alpha/beta hydrolase domain-containing protein 15, Protein ABHD15



经过测试的应用

Positive WB detected inmouse lung tissue, Transfected HEK-293 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 22526-1-AP is ABHD15 Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA
Cited ApplicationsWB
Tested Reactivity human, mouse
Cited Reactivitymouse
Immunogen ABHD15 fusion protein Ag18334 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name abhydrolase domain containing 15
Synonyms ABHD15, Abhydrolase domain-containing protein 15, Alpha/beta hydrolase domain-containing protein 15, Protein ABHD15
Calculated Molecular Weight 468 aa, 52 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberBC012476
Gene Symbol ABHD15
Gene ID (NCBI) 116236
RRIDAB_2879117
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6UXT9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ABHD15 belongs to the α/β-hydrolase superfamily which consists of various lipases, esterases, and proteases that share an α/β fold as a common structural feature. ABHD15 is highly expressed in adipose tissues and is required for the anti-lipolytic action of INS in white adipose tissue (WAT). ABHD15 expression is decreased in humans with obesity and diabetes compared to humans with obesity and normal glucose tolerance, identifying ABHD15 as a potential therapeutic target to mitigate INS resistance (PMID: 29768196).

实验方案

Product Specific Protocols
WB protocol for ABHD15 antibody 22526-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Cell Rep

PMID: 29768196

Authors - Wenmin Xia
  • KO Validated
mouseWB

Mol Metab

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation.

Authors - Jacqueline Stöckli
  • KO Validated