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AID Polyclonal antibody

AID Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

ELISA

Conjugate

Unconjugated

Cat No : 15642-1-AP

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Synonyms

AICDA, AID, ARP2, CDA2, Cytidine aminohydrolase, HIGM2

验证数据展示

产品信息

15642-1-AP targets AID in ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications ELISA
Tested Reactivity human, mouse, rat
Immunogen AID fusion protein Ag8136 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name activation-induced cytidine deaminase
Synonyms AICDA, AID, ARP2, CDA2, Cytidine aminohydrolase, HIGM2
Calculated Molecular Weight 198 aa, 24 kDa
Observed Molecular Weight48-52 kDa
GenBank Accession NumberBC006296
Gene Symbol AICDA
Gene ID (NCBI) 57379
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9GZX7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

AID is essential to all three genetic alterations required for antigen-specific immunoglobulin: class switch recombination (CSR), somatic bypermutation (SHM), and gene conversion. Expression of AID is normally restricted to B cells in the GC, where SHM and CSR occur. It is likely these represent AID monomer and homodimer that western blot detected two bands in purified AID from nuclear extracts, one at 52 kDa and the other at 26 kDa. (PMID:16280388)