ASF/SF2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66671-1-Ig |CloneNo.: 1A6C5

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
Human, mouse, rat

Positive WB detected in:
HeLa cells

Recommended dilution:
WB : 1:5000-1:50000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
splicing factor, arginine/serine-rich 1

Calculated molecular weight:
248aa,28 kDa

Observed molecular weight:
32, 28, 22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SFRS1

Synonyms
Alternative splicing factor 1, ASF, ASF 1, ASF/SF2, SF2, SF2p33, SFRS1, SRp30a, SRSF1
Background

SFRS1, also named as ASF, SF2, SF2P33, SFRS1 and ASF-1, belongs to the splicing factor SR family. It plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. SFRS1 interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. This antibody can recognize all the 3 isoforms(28kd,33kd and 22kd) of SFRS1.


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