BAG1S/1M/1L Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 16150-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, Jurkat cells, mouse brain tissue, mouse liver tissue

Positive IHC detected in:
human testis tissue, human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue, human testis tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
BCL2-associated athanogene

Calculated molecular weight:
26 kDa

Observed molecular weight:
46-50 kDa, 41-46 kDa, 25-33 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BAG1

Synonyms
Background

BAG1 have been identified that modulate gene transcription through poorly defined mechanisms. Four isoforms of the BAG1 protein (BAG1S, BAG1, BAG1M and BAG1L) can be produced from a common mRNA by use of alternative translation initiation sites, including a non-canonical CTG codon in one instance. The longest, BAG1L (Mr ~50K), contains a nuclear localization signal (NLS) and resides in the nucleus, whereas BAG1M (Mr ~46K) has an incomplete NLS and distributes mainly in cytosol, unless dragged into the nucleus through interactions with other. Distribution of BAG1S(p33) is not clear yet. This antibody recongizes all the isoforms of BAG1, includes GAG1L, BAG1V, BAG1M and BAG1S.


Back
to top