PE Anti-Mouse CD127 (IL-7Ra) (A7R34)

CD127 (IL-7Ra) Monoclonal Antibody for FC

Host / Isotype

Rat / IgG2a

Reactivity

Mouse and More (1)

Applications

FC

Conjugate

PE Fluorescent Dye

CloneNo.

A7R34

Cat No : PE-65093

Print datasheet

Synonyms

CD127, IL 7Ralpha, IL- 7Ralpha, Il7r, IL-7Ra, interleukin 7 receptor



经过测试的应用

Positive FC detected inmouse splenocytes

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

发表文章中的应用

FCSee 1 publications below

产品信息

PE-65093 targets CD127 (IL-7Ra) in FC applications and shows reactivity with Mouse samples.

Tested Applications FC
Cited Applications FC
Tested Reactivity Mouse
Cited Reactivitymouse
Immunogen IL-7Ra-IgG1 fusion protein 种属同源性预测
Host / Isotype Rat / IgG2a
Class Monoclonal
Type Antibody
Full Name interleukin 7 receptor
Synonyms CD127, IL 7Ralpha, IL- 7Ralpha, Il7r, IL-7Ra, interleukin 7 receptor
GenBank accession numberBC089571
Gene symbol Il7r
UniprotP16872
Gene ID (NCBI) 16197
RRIDAB_2883887
Conjugate PE Fluorescent Dye
Excitation/Emission maxima wavelengths496 nm, 565 nm / 578 nm
Form Liquid
Purification Method Affinity purification
Storage Buffer Phosphate based buffer with 0.09% sodium azide and 0.1% gelatin, pH 7.2.
Storage ConditionsStore at 2-8°C. Avoid exposure to light.

背景介绍

CD127, also known as IL-7R subunit alpha (IL-7Rα), is a type I membrane glycoprotein expressed on thymocytes, B cell precursors, most T cells, and some lymphoid and myeloid cells (PMID: 8415665). IL-7R is a heterodimer composed of CD127 and IL-2Rγ (CD132), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15 (PMID: 8266077; 9862091). IL-7R plays critical roles in lymphocyte development and homeostasis (PMID: 26336149). CD127 can also act as a receptor for thymic stromal lymphopoietin (TSLP) (PMID: 10974032).

实验方案

Product Specific Protocols
FC protocol for PE CD127 (IL-7Ra) antibody PE-65093Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseFC

J Inflamm Res

Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway

Authors - Yuan Cao