YF594-conjugated CD3 Antibody 0 Publications

Mouse Monoclonal| Catalog number: YF594-60181 |CloneNo.: 3F3A1

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human

Positive IF detected in:
human tonsillitis tissue

Recommended dilution:
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD3e molecule, epsilon (CD3-TCR complex)

Calculated molecular weight:
207aa,23 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD3E

Synonyms
CD3E, T3E, TCRE
Background

CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.


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