CIDEC Polyclonal antibody
CIDEC Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | MCF-7 cells, L02 cells |
Planning an IHC experiment? We recommend our IHCeasy CIDEC Ready-To-Use IHC Kit. CIDEC primary antibody included.
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 6 publications below |
产品信息
12287-1-AP targets CIDEC in WB,ELISA applications and shows reactivity with human samples.
| Tested Applications | WB, ELISA |
| Cited Applications | WB |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Immunogen | CIDEC fusion protein Ag2913 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | cell death-inducing DFFA-like effector c |
| Synonyms | Cell death activator CIDE 3, CIDE 3, CIDEC, Fsp27 |
| Calculated Molecular Weight | 238 aa, 27 kDa |
| Observed Molecular Weight | 27-35 kDa |
| GenBank Accession Number | BC016851 |
| Gene Symbol | CIDEC |
| Gene ID (NCBI) | 63924 |
| RRID | AB_2877842 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96AQ7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Cell death-inducing DFF45-like effector (CIDE) proteins, including CIDEA, CIDEB and CIDEC (also called Fsp27 in rodents), are predominantly expressed in brown adipose tissues (BAT), liver and WAT. CIDEC was found to be highly expressed in adipose tissues and to function as a lipid droplet-binding protein that promotes lipid accumulation in adipocytes. While normal mouse livers express low levels of CIDEC protein, its expression is highly upregulated in NALFD, but not in chronic ethanol feeding-induced fatty liver. (PMID: 26099526) Catalog#12287-1-AP recognizing CIDEC (calculated 28 kDa) as a 30 kDa and 45-50 kDa due to its posttranslational modification (PMID: 19258494).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for CIDEC antibody 12287-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Nutr Biochem Identification of potential pathogenic hepatic super-enhancers regulatory network in high-fat diet induced hyperlipidemia | ||
Commun Biol Glutathione S-transferase Mu 2 inhibits hepatic steatosis via ASK1 suppression. | ||
Cancer Biol Ther The facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer | ||
Biomed Pharmacother Dihydroartemisinin inhibits ER stress-mediated mitochondrial pathway to attenuate hepatocyte lipoapoptosis via blocking the activation of the PI3K/Akt pathway. | ||
Aging Cell Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice | ||
Cell Death Discov Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway |
