CP110 Antibody 36 Publications

Rabbit Polyclonal| Catalog number: 12780-1-AP

Featured Product KD/KO validated

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse, rat, dog, Xenopus

Positive WB detected in:
HeLa cells, K-562 cells

Positive IP detected in:
HeLa cells, multi-cells

Positive IHC detected in:
human prostate cancer tissue

Positive IF detected in:
MEF/HeLa cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:5000
IP : 0.5-4.0 ug for IP and 1:500-1:5000 for WB
IHC : 1:100-1:400
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CP110 protein

Calculated molecular weight:
991aa,111 kDa

Observed molecular weight:
113 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CP110

Synonyms
Centrosomal protein of 110 kDa, CP110, CP110 protein, DKFZp781G1416, KIAA0419
Background

CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.


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