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CX3CL1 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 10108-2-AP

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浓度: 150μg/ml

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Related Primary Antibodies

Tested Applications

Applications:
WB, IHC, ELISA
Application not tested? Please see our Guarantee


Images See all

CX3CL1 Antibody WB PC-3 cells 10108-2-AP

PC-3 cells were subjected to SDS PAGE followed by western blot with 10108-2-AP(CX3CL1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours

CX3CL1 Antibody IHC human small intestine tissue 10108-2-AP

Immunohistochemistry of paraffin-embedded human small intestine slide using 10108-2-AP( CX3CL1 Antibody) at dilution of 1:50 (under 10x lens)

CX3CL1 Antibody IHC human small intestine tissue 10108-2-AP

Immunohistochemistry of paraffin-embedded human small intestine slide using 10108-2-AP( CX3CL1 Antibody) at dilution of 1:50 (under 40x lens)

Species specificity:
human
Positive WB detected in:
PC-3 cells, human brain tissue
Positive IHC detected in:
human small intestine tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
CX3CL1 fusion protein Ag0161
Full name:
chemokine (C-X3-C motif) ligand 1
Calculated molecular weight:
42 kDa
Observed molecular weight:
90-100 kDa
GenBank accession number:
BC001163
Gene ID (NCBI):
6376
Gene symbol
CX3CL1
Synonyms
ABCD 3, C X3 C motif chemokine 1, C3Xkine, CX3CL1, CXC3, CXC3C, FKN, fractalkine, neurotactin, NTN, NTT, SCYD1, Small inducible cytokine D1

Background

Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key role in inflammatory and infectious diseases such as AIDS. The human CX3C chemokine carries the chemokine domain on top of an extended mucin-like stalk. CX3CL1 is synthesized as a 50-75kDa precursor and undergoes glycosylation to yield two mature forms: a 100kDa cell membrane bound form and an 85kDa soluble form which is released from the cell surface.The soluble CX3C chemokine has potent chemoattractant activity for T cells and monocytes, and the cell-surface-bound protein, which is induced by primary proinflammatory signals in activated primary endothelial cells, promotes strong adhesion of those leukocytes.


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