YF594-conjugated Cytokeratin 18 Antibody 0 Publications

Mouse Monoclonal| Catalog number: YF594-66187 |CloneNo.: 1G11C4

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human

Positive IF detected in:
HepG2 cells

Recommended dilution:
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3 Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
keratin 18

Calculated molecular weight:
48 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT18

Synonyms
CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18
Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.


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