G3BP Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66486-1-Ig |CloneNo.: 1E4A2

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
Human, mouse, rat, pig

Positive WB detected in:
HeLa cells, pig brain tissue, mouse brain tissue

Positive IHC detected in:
human testis tissue, human lymphoma tissue, human colon tissue

Recommended dilution:
WB : 1:5000-1:10000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
N/A

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
GTPase activating protein (SH3 domain) binding protein 1

Calculated molecular weight:
466aa,52 kDa

Observed molecular weight:
68 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
G3BP1

Synonyms
G3BP, G3BP 1, G3BP1, HDH VIII
Background

GAP SH3 Binding Protein 1 (G3BP1), also named as G3BP, is an effector of stress granule (SG) assembly. SG biology plays an important role in the pathophysiology of TDP-43 in ALS and FTLD-U. G3BP1 can be used as a marker of SG. It has been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation. G3BP1 is a ubiquitously expressed protein that localizes to the cytoplasm in proliferating cells and to the nucleus in non-proliferating cells. G3BP1 has recently been implicated in cancer biology.


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