IMP3 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 12750-1-AP

Featured Product KD/KO validated

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, MCF-7 cells

Positive IP detected in:
HeLa cells

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)

Calculated molecular weight:
184aa,22 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IMP3

Synonyms
BRMS2, C15orf12, IMP3, MRPS4, U3 snoRNP protein IMP3
Background

IMP3 is a member of the insulin-like growth factor (IGF-II) mRNA binding protein (IMP) family that consist of IMP1, IMP2, and IMP3. IMP3 is an oncofetal protein associated with aggressive and advanced tumors and is specifically expressed in malignant tumors but not found in benign tissues [PMID:22497850]. IMP3 forms a ternary complex with IMP4 and MPP10 (MPHOSPH10) that interacts with U3 small nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing[PMID: 12655004].


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