TAX1BP1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14424-1-AP

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse

Positive WB detected in:
HEK-293 cells, HepG2 cells, mouse kidney tissue, mouse liver tissue, mouse lung tissue, mouse testis tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Tax1 (human T-cell leukemia virus type I) binding protein 1

Calculated molecular weight:
91 kDa

Observed molecular weight:
68 kDa, 85 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TAX1BP1

Synonyms
CALCOCO3, T6BP, Tax1 binding protein 1, TAX1BP1, TRAF6 binding protein, TXBP151
Background

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms with MW 65-68 kDa and 86-91 kDa. Western blot analysis showed that TAX1BP1 is expressed as an 86 kDa or a 68 kDa protein.


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