TRAF4 Polyclonal antibody

TRAF4 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

ELISA and More (1)

Conjugate

Unconjugated

Cat No : 10083-2-AP

Print datasheet

Synonyms

CART1, MLN 62, MLN62, RING finger protein 83, RNF83, TRAF4



经过测试的应用

推荐稀释比

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IHCSee 1 publications below

产品信息

10083-2-AP targets TRAF4 in IHC,ELISA applications and shows reactivity with human samples.

Tested Applications ELISA
Cited Applications IHC
Tested Reactivity human
Cited Reactivityhuman
Immunogen TRAF4 fusion protein Ag0121 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name TNF receptor-associated factor 4
Synonyms CART1, MLN 62, MLN62, RING finger protein 83, RNF83, TRAF4
Calculated Molecular Weight 54 kDa
GenBank Accession NumberBC001769
Gene Symbol TRAF4
Gene ID (NCBI) 9618
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9BUZ4
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TRAF4 is the fourth member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with and mediate signal transduction from members of the TNF receptor superfamily. TRAF1 and TRAF2 are two related proteins that form a heterodimeric complex that associates with the cytoplasmic domain of the TNF-receptor type 2. The third member TRAF3 associates with the cytoplasmic domain of CD40. TRAF4 has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-KAPPA B activation. This protein also binds to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. TRAF4 thus, is thought to be involved in the oxidative activation of MAPK8/JNK.

发表文章

SpeciesApplicationTitle
humanIHC

Cell Death Dis

Nonenzymatic function of Aldolase A downregulates miR-145 to promote the Oct4/DUSP4/TRAF4 axis and the acquisition of lung cancer stemness.

Authors - Yu-Chan Chang