TRAF4 Polyclonal antibody
TRAF4 Polyclonal Antibody for ELISA
验证数据展示
经过测试的应用
推荐稀释比
Application | Dilution |
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It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
IHC | See 1 publications below |
产品信息
10083-2-AP targets TRAF4 in IHC,ELISA applications and shows reactivity with human samples.
Tested Applications | ELISA |
Cited Applications | IHC |
Tested Reactivity | human |
Cited Reactivity | human |
Immunogen | TRAF4 fusion protein Ag0121 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | TNF receptor-associated factor 4 |
Synonyms | CART1, MLN 62, MLN62, RING finger protein 83, RNF83, TRAF4 |
Calculated Molecular Weight | 54 kDa |
GenBank Accession Number | BC001769 |
Gene Symbol | TRAF4 |
Gene ID (NCBI) | 9618 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9BUZ4 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TRAF4 is the fourth member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with and mediate signal transduction from members of the TNF receptor superfamily. TRAF1 and TRAF2 are two related proteins that form a heterodimeric complex that associates with the cytoplasmic domain of the TNF-receptor type 2. The third member TRAF3 associates with the cytoplasmic domain of CD40. TRAF4 has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-KAPPA B activation. This protein also binds to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. TRAF4 thus, is thought to be involved in the oxidative activation of MAPK8/JNK.
发表文章
Species | Application | Title |
---|---|---|
Cell Death Dis Nonenzymatic function of Aldolase A downregulates miR-145 to promote the Oct4/DUSP4/TRAF4 axis and the acquisition of lung cancer stemness. |