WDR24 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 20778-1-AP

Featured Product KD/KO validated

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse

Positive WB detected in:
HeLa cells, mouse brain tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human ovary tissue, human colon tissue, human ovary tissue

Positive IF detected in:
Hela cells, HepG2 cells

Recommended dilution:
WB : 1:500-1:5000
IP : 0.5-4.0 ug for IP and 1:200-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
WD repeat domain 24

Calculated molecular weight:
920aa,102 kDa

Observed molecular weight:
102 kDa,88 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
WDR24

Synonyms
C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24
Background

WDR24 is a component of the GATOR2 complex which has five known subunits (WDR24, WDR59, Mios, Sec13, and Seh1L). GATOR2 complex positively regulates mTORC1 signaling by acting upstream of or in parallel to GATOR1, which is a GTPase-activating protein (GAP) for RagA or RagB and an inhibitor of the amino-acid-sensing pathway. (PMID: 23723238; 25263562)


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