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CoraLite®488-conjugated ARL13B Polyclonal antibody

ARL13B Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat, Canine

Applications

IF

Conjugate

CoraLite®488 Fluorescent Dye

Cat No : CL488-17711

Print datasheet

Synonyms

ARL13B, ARL2 like protein 1, ARL2L1, DKFZp686E2075, DKFZp686L2472, DKFZp686M2074, DKFZp761H079, JBTS8



经过测试的应用

Positive IF detected inMDCK cells
For other applications, we recommend the unconjugated version of this antibody, 17711-1-AP

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:25-1:100
Sample-dependent, check data in validation data gallery

发表文章中的应用

IFSee 1 publications below

产品信息

CL488-17711 targets ARL13B in IF applications and shows reactivity with human, mouse, rat, Canine samples.

Tested Applications IF
Cited Applications IF
Tested Reactivity human, mouse, rat, Canine
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ARL13B fusion protein Ag12015
Full Name ADP-ribosylation factor-like 13B
Synonyms ARL13B, ARL2 like protein 1, ARL2L1, DKFZp686E2075, DKFZp686L2472, DKFZp686M2074, DKFZp761H079, JBTS8
Calculated molecular weight 48 kDa
GenBank accession numberBC094725
Gene symbol ARL13B
UniprotQ3SXY8
Gene ID (NCBI) 200894
RRIDAB_2883085
Conjugate CoraLite®488 Fluorescent Dye
Excitation/Emission maxima wavelengths488 nm / 515 nm
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

背景介绍

ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). CoraLite488-Conjugated ARL13B antibody can be used to mark the cilia(green). Ex: 488nm, Em: 515nm

实验方案

Product Specific Protocols
IF protocol for CL488 ARL13B antibody CL488-17711Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF

Neurosci Res

Phenotypic characterization of Cdkl5-knockdown neurons establishes elongated cilia as a functional assay for CDKL5 Deficiency Disorder.

Authors - Alessia Di Nardo