• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

G6PDi-1

G6PDi-1 是一种有效的 G6PD 抑制剂。它消耗 NADPH 并减少炎性细胞因子的产生。

CAS号

2457232-14-1

分子式

C14H12N4OS

主要靶点

Dehydrogenase

仅限科研使用

Cat No : CM03644

Print datasheet

Synonyms

验证数据展示

  • CAS No.: 2457232-14-1

    G6PDi-1
    CAS#: 2457232-14-1

产品信息

G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.

CAS号 2457232-14-1
分子式 C14H12N4OS
主要靶点 Dehydrogenase
主要通路 代谢
分子量 284.34
纯度 98.69%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

体外活性

G6PDi-1 effectively inhibits G6PD.?Across a range of cultured cells, G6PDi-1 depletes NADPH most strongly in lymphocytes.?In T cells but not macrophages, G6PDi-1 markedly decreases inflammatory cytokine production.?In neutrophils, it suppresses respiratory burst.

溶解度

DMSO:25 mg/mL (87.92 mM)

参考文献

1.Ghergurovich J M , Juan C. García-Caaveras, Wang J , et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway[J]. Nature Chemical Biology, 2020, 16(7):1-9.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2