CoraLite®647-conjugated GRP94 Polyclonal antibody
GRP94 Polyclonal Antibody for
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
Conjugate
CoraLite® Plus 647 Fluorescent Dye
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy GRP94/HSP90B1 Ready-To-Use IHC Kit. GRP94/HSP90B1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 14700-1-AP
产品信息
CL650-14700 targets GRP94 in applications and shows reactivity with human, mouse, rat samples.
Tested Applications | Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | GRP94 fusion protein Ag6344 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | heat shock protein 90kDa beta (Grp94), member 1 |
Synonyms | Cell and organelle markers, ECGP, endoplasmic reticulum marker, Endoplasmin, GP96, gp96 homolog, GRP 94, GRP94, HSP90B1, TRA1, Tumor rejection antigen 1 |
Calculated Molecular Weight | 92 kDa |
Observed Molecular Weight | 100 kDa |
GenBank Accession Number | BC066656 |
Gene Symbol | GRP94 |
Gene ID (NCBI) | 7184 |
RRID | AB_2920403 |
Conjugate | CoraLite® Plus 647 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 654 nm / 674 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P14625 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HSP90 proteins are highly conserved molecular chaperones, which normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 (GP96 or GRP94) is an endoplasmic reticulum paralogue of the cytosolic HSP90. As a major ER chaperone to mediate the UPR and a master chaperone for Toll-like receptors (TLRs), HSP90b1 chaperones peptides to MHC class I molecules of dendritic cells and other antigen-presenting cells, as well as facilitating the assembly of immunoglobulin. The protein is also involved in many other bio-processes. This antibody was generated against the C-terminal region of full-length HSP90b1.
实验方案
Product Specific Protocols | |
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FC protocol for CL Plus 647 GRP94 antibody CL650-14700 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |