CD34 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 60180-1-Ig |CloneNo.: 3C8G12

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Species specificity:
human

Positive WB detected in:
human placenta tissue

Positive IHC detected in:
human tonsillitis tissue, human liver cancer tissue, human placenta tissue, human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Caprylic acid/ammonium sulfate precipitation

Isotype:
IgG2b

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD34 molecule

Calculated molecular weight:
41 kDa

Observed molecular weight:
105-120 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD34

Synonyms
CD34, CD34 molecule
Background

CD34 is a 105- to 120-kDa glycophosphoprotein expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nerve tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources. Along with other positive selection markers (such as CD29, CD44, CD90, CD105 and CD166), negative selection markers (such as CD34 and CD45) are used for MSC identification.


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