Cytochrome c Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66264-1-Ig |CloneNo.: 2D8D11

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, human heart tissue, human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human liver cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:5000-1:50000
IHC : 1:20-1:800
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cytochrome c, somatic

Calculated molecular weight:
12 kDa

Observed molecular weight:
12-15 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CYCS

Synonyms
CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4
Background

Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.


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