NSE Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66150-1-Ig |CloneNo.: 6F8G3

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse, rat, pig

Positive WB detected in:
U-251 cells, C6 cells, fetal human brain tissue, Neuro-2a cells, pig brain tissue, rat brain tissue, SH-SY5Y cells

Positive IHC detected in:
human brain tissue

Positive IF detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:1000-1:8000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
enolase 2 (gamma, neuronal)

Calculated molecular weight:
47 kDa

Observed molecular weight:
47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ENO2

Synonyms
ENO2, Enolase 2, enolase 2 (gamma, neuronal), Gamma enolase, Neural enolase, Neuron specific enolase, NSE
Background

NSE, also named as ENO2, belongs to the enolase family. Enolases are cytoplasmic glycolytic enzymes that may be involved in differentiation. The enolase has three isoenzymes, alpha, beta and gamma. The alpha form is expressed in most tissues, whereas the beta form is expressed in muscle tissue. The gamma enolase (ENO2), a homodimer, is primarily localized in neurons and neuroendocrine cells and is a cancer diagnostic marker for brain tumors (PMID:7520111). ENO2 plays a role in the glycolysis-related energy pathway and might be involved in higher metabolic activity during the day than at night, at least in part.


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