|Cell culture supernatant||90%||82%-102%|
Protein ST2, also known as IL1RL1, DER4 and T1, is a member of the interleukin 1 receptor family. The gene of ST2 encodes three splice variants: a soluble secreted form, a transmembrane form and a form of undetermined localization. In some ELISA study on patients with autoimmune diseases, the hST2 concentration of some, but not all, sera of patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Wegener’s granulomatosis, and Behc¸et disease were markedly higher than those of healthy controls. ST2 protein should be important both to fundamental researches and the further clarification of the clinical implications of the ST2 protein.