验证数据展示
产品信息
12962-1-AP targets IL-15 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA Application Description |
| Tested Reactivity | human, mouse, rat |
| Immunogen | IL-15 fusion protein Ag3650 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | interleukin 15 |
| Synonyms | IL15, Interleukin-15, IL 15 |
| Calculated Molecular Weight | 18 kDa |
| GenBank Accession Number | BC018149 |
| Gene Symbol | IL15 |
| Gene ID (NCBI) | 3600 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P40933 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Interleukin 15 (IL15) is a cytokine important for the development, maturation, and function of many cells of the immune system including NK, NKT, gammadeltaT, and CD8(+) T cells. Its expression affects homeostasis and function of B cells through NK cell-derived IFNG. IL-15 binds a trimeric IL-15 receptor (IL-15R) complex formed by a specific receptor chain (IL-15Rα) combined with theβandγchains of the IL-2R, acting as signal transducing components. High levels of IL15 expression have been associated with the pathogenesis of autoimmune and inflammatory diseases like Crohn's disease, psoriasis, leukemias, rheumatoid arthritis (RA) and graft rejection, resulting in the IL15 system being a target of interest for the treatment of these diseases.