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IL-15 Polyclonal antibody

IL15 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat No : 12962-1-AP

Print datasheet

Synonyms

IL 15, IL15, interleukin 15

验证数据展示

  • IHC staining of human lung cancer using 12962-1-AP

    IHC staining of human lung cancer using 12962-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer using 12962-1-AP (IL15 antibody) at dilution of 1:100 (under 10x lens).

产品信息

12962-1-AP targets IL15 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen IL15 fusion protein Ag3650 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name interleukin 15
Synonyms IL 15, IL15, interleukin 15
Calculated Molecular Weight 18 kDa
GenBank Accession NumberBC018149
Gene Symbol IL15
Gene ID (NCBI) 3600
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP40933
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Interleukin 15 (IL15) is a cytokine important for the development, maturation, and function of many cells of the immune system including NK, NKT, gammadeltaT, and CD8(+) T cells. Its expression affects homeostasis and function of B cells through NK cell-derived IFNG. IL-15 binds a trimeric IL-15 receptor (IL-15R) complex formed by a specific receptor chain (IL-15Rα) combined with theβandγchains of the IL-2R, acting as signal transducing components. High levels of IL15 expression have been associated with the pathogenesis of autoimmune and inflammatory diseases like Crohn’s disease, psoriasis, leukemias, rheumatoid arthritis (RA) and graft rejection, resulting in the IL15 system being a target of interest for the treatment of these diseases.