验证数据展示
经过测试的应用
| Positive WB detected in | mouse skeletal muscle tissue, rat skeletal muscle tissue |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 2 publications below |
产品信息
17678-1-AP targets MSX1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | WB, ELISA Application Description |
| Cited Applications | WB |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Immunogen | MSX1 fusion protein Ag11700 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | msh homeobox 1 |
| Synonyms | Homeobox protein Hox 7, Homeobox protein MSX 1, HOX7, HYD1, msh homeobox 1, Msh homeobox 1 like protein, MSX1 |
| Calculated Molecular Weight | 303 aa, 32 kDa |
| Observed Molecular Weight | 32 kDa |
| GenBank Accession Number | BC021285 |
| Gene Symbol | MSX1 |
| Gene ID (NCBI) | 4487 |
| RRID | AB_2878426 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P28360 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MSX1, also known as, Homeobox protein Hox-7 or Msh homeobox 1-like protein, is a 303 maino acid protein, which plays an important role during embryogenesis. Msx1 was the first mammalian member of the Msx subfamily of homeobox genes that was described,and it was isolated from a cDNA library prepared from mouse 8.5-day embryos. Expression of Msx1 has been described during embryogenesis of limb buds, genital ridges, visceral arches, craniofacial structures, central nervous system, and the developing pituitary gland. Msx1 expression in adult mouse uterus and mammary gland has also been reported recently. (PMID: 9369446). MSX1 displays homology to the Drosophilamuscle segment homeobox (msh) gene, which is important in development. MSX1 encodes important genes that regulate numerous morphogenic events, such as tooth formation, bone development, development of the central nervous system, and the development and proliferation of various cell types (PMID: 18379900) .
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for MSX1 antibody 17678-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Oncogene LINC01021 maintains tumorigenicity by enhancing N6-methyladenosine reader IMP2 dependent stabilization of MSX1 and JARID2: implication in colorectal cancer. | ||
Stem Cells Int Noggin Combined With Human Dental Pulp Stem Cells to Promote Skeletal Muscle Regeneration |
