P53 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 60283-1-Ig |CloneNo.: 2D2F10

Featured Product KD/KO validated

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Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, HEK-293 cells, COLO 320 cells, RAW 264.7 cells, NIH/3T3 cells,

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human ovary tumor tissue, human gliomas tissue

Recommended dilution:
WB : 1:2000-1:20000
IP : 0.5-4.0 ug for IP and 1:500-1:3000 for WB
IHC : 1:50-1:500

Product Information


Purification method:
Protein G purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
tumor protein p53

Calculated molecular weight:
44 kDa

Observed molecular weight:
53 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, Phosphoprotein p53, TRP53, tumor protein p53, Tumor suppressor p53

TP53, also named as P53 and NY-CO-13, belongs to the p53 family. It has 9 isoforms. In SDS-Page, the MW is about 53kd. TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. The antibody reacts specifically with 53 kDa protein.

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