PPARGC1A Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66369-1-Ig |CloneNo.: 1C1B2

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Species specificity:
human, mouse, rat

Positive WB detected in:
C2C12 cell

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:6000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Calculated molecular weight:
91 kDa

Observed molecular weight:
100 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PPARGC1A

Synonyms
LEM6, Ligand effect modulator 6, PGC 1 alpha, PGC 1(alpha), PGC 1v, PGC1, PGC1A, PPAR gamma coactivator 1 alpha, PPARGC 1 alpha, PPARGC1, PPARGC1A
Background

PPARGC1A, also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, is a 798 amino acid protein, which Contains 1 RRM (RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. PPARGC1A exists various isoforms and range of molecular weight of isoforms are 30-50 kDa and 90-110 kDa.


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