PTEN Antibody 6 Publications

Mouse Monoclonal| Catalog number: 60300-1-Ig |CloneNo.: 5C10B6

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse

Positive WB detected in:
fetal human brain tissue, DU 145 cells, fetal human brain tissue, HeLa cells, RAW 264.7 cells

Positive IHC detected in:
human breast hyperplasia tissue, human breast cancer tissue, human breast hyperplasia tissue, human endometrial cancer tissue, human lung cancer tissue, human prostate hyperplasia tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:10000
IHC : 1:200-1:1200
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
phosphatase and tensin homolog

Calculated molecular weight:
47 kDa

Observed molecular weight:
55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PTEN

Synonyms
10q23del, BZS, MHAM, MMAC1, phosphatase and tensin homolog, PTEN, PTEN1, TEP1
Background

PTEN (also designated MMAC1), products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast, kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol.


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