验证数据展示
产品信息
17781-1-AP targets RSPO2 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IF, IHC |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, pig |
| 免疫原 | RSPO2 fusion protein Ag11216 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | R-spondin 2 homolog (Xenopus laevis) |
| 别名 | CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 |
| 计算分子量 | 243 aa, 28 kDa |
| 观测分子量 | 33 kDa |
| GenBank蛋白编号 | BC027938 |
| 基因名称 | RSPO2 |
| Gene ID (NCBI) | 340419 |
| RRID | AB_2269700 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6UXX9 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
RSPO2 is one of the R-spondins (RSPOs) which comprise a family of four secreted proteins that have important roles in cell proliferation, cell fate determination and organogenesis. RSPOs typically exert their effects by potentiating the Wnt/beta-catenin signaling pathway. Overexpression of Rspo2 is sufficient to promote bone morphogenetic protein-induced mineralization Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse mammary tumors.
发表文章
| Species | Application | Title |
|---|---|---|
Int J Mol Sci R-Spondin2, a Positive Canonical WNT Signaling Regulator, Controls the Expansion and Differentiation of Distal Lung Epithelial Stem/Progenitor Cells in Mice. | ||
DNA Cell Biol Expression and Prognostic Values of the Roof Plate-Specific Spondin Family in Bladder Cancer. | ||
BMC Res Notes R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability.
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