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TH Monoclonal antibody

TH Monoclonal Antibody for WB, IF/ICC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IF/ICC, ELISA and More (2)

Conjugate

Unconjugated

CloneNo.

2H7B7

Cat no : 66334-1-Ig

Print datasheet

Synonyms

TH, TYH, Tyrosine 3 hydroxylase, Tyrosine 3 monooxygenase, tyrosine hydroxylase



经过测试的应用

Positive WB detected inPC-12 cells, SH-SY5Y cells
Positive IF/ICC detected inSH-SY5Y cells
Planning an IHC experiment? We recommend our IHCeasy TH Ready-To-Use IHC Kit. TH primary antibody included.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:3000-1:20000
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

66334-1-Ig targets TH in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, ELISA Application Description
Cited ApplicationsWB, IHC, IF
Tested Reactivity human
Cited Reactivityhuman
Immunogen TH fusion protein Ag23075 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name tyrosine hydroxylase
Synonyms TH, TYH, Tyrosine 3 hydroxylase, Tyrosine 3 monooxygenase, tyrosine hydroxylase
Calculated Molecular Weight 528 aa, 59 kDa
Observed Molecular Weight 55 kDa
GenBank Accession NumberBC104967
Gene Symbol TH
Gene ID (NCBI) 7054
RRIDAB_2881714
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP07101
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TH(Tyrosine 3-monooxygenase) converts L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA), the essential and rate-limiting step to formation of DA and other catecholamines. TH plays an important role in the physiology of adrenergic neurons and can be used as a marker for DA and noradrenergic neurons.

实验方案

Product Specific Protocols
WB protocol for TH antibody 66334-1-IgDownload protocol
IF protocol for TH antibody 66334-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Mol Oncol

Norepinephrine-CREB1-miR-373 axis promotes progression of colon cancer.

Authors - Jia Han
WB

Front Cell Dev Biol

RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy.

Authors - Mengxi Niu
humanIF

Antioxidants (Basel)

Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency

Authors - Xiao Sun
WB,IF

Bone Joint Res

High-intensity interval training improves fatty infiltration in the rotator cuff through the β3 adrenergic receptor in mice

Authors - Hecheng Zhou
IHC

Biomed Pharmacother

Nardosinone regulates the slc38a2 gene to alleviate Parkinson's symptoms in rats through the GABAergic synaptic and cAMP pathways.

Authors - Li-Hua Bian
IHC

J Neuropathol Exp Neurol

Regular Aerobic Exercise-Alleviated Dysregulation of CAMKIIα Carbonylation to Mitigate Parkinsonism via Homeostasis of Apoptosis With Autophagy.

Authors - Wenfeng Liu