VCAM-1 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66294-1-Ig |CloneNo.: 1B12F12

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Species specificity:
human, mouse

Positive WB detected in:
human spleen tissue

Positive IHC detected in:
human lung cancer tissue, human lung cancer tissue, human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
vascular cell adhesion molecule 1

Calculated molecular weight:
739aa,81 kDa

Observed molecular weight:
110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
VCAM1

Synonyms
CD106, DKFZp779G2333, INCAM 100, L1CAM, V CAM 1, VCAM 1, VCAM1, VCAM-1
Background

Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).


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