WTAP Antibody 4 Publications

Mouse Monoclonal| Catalog number: 60188-1-Ig |CloneNo.: 4A10G9

Featured Product KD/KO validated

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, HepG2 cells, HeLa cells, fetal human brain tissue, mouse testis tissue, human testis tissue, Jurkat cells

Positive IHC detected in:
human cervical cancer tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:6000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Wilms tumor 1 associated protein

Calculated molecular weight:
45 kDa

Observed molecular weight:
50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
WTAP

Synonyms
DKFZp686F20131, Female lethal(2)D homolog, hFL(2)D, KIAA0105, WT1 associated protein, WTAP
Background

WTAP, also named as KIAA0105 and hFL(2)D, is previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. It is a Pre-mRNA-splicing regulator protein. It is a regulatory subunit of the WMM N6-methyltransferase complex which plays a role in the efficiency of mRNA splicing and processing and mRNA stability. It is required for accumulation of METTL3 and METTL14 to nuclear speckle.


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