c-SRC Antibody 3 Publications

Mouse Monoclonal| Catalog number: 60315-1-Ig |CloneNo.: 5E10C4

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, hamster, mouse

Positive WB detected in:
HeLa cells, CHO cells, HEK-293 cells, RAW 264.7 cells

Positive IHC detected in:
human breast cancer tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:1000-1:8000
IHC : 1:100-1:400
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Calculated molecular weight:
60 kDa

Observed molecular weight:
60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SRC

Synonyms
ASV, c SRC, c-SRC, p60 Src, pp60c src, Proto oncogene c Src, SRC, SRC1
Background

SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.


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