14-3-3 GAMMA-Specific Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 12381-1-AP

Featured Product KD/KO validated

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50 μl


100 μl


150 μl


Species specificity:
human, mouse, rat, dog

Positive WB detected in:
mouse IMCD3 cells (RNAi), A431 cells

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human lung cancer tissue, human breast cancer tissue

Positive IF detected in:
MDCK cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide

Calculated molecular weight:
247aa,28 kDa

Observed molecular weight:
28-33 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

14 3 3 protein gamma, 14 3 3GAMMA, 14-3-3, 14-3-3 GAMMA, KCIP 1, YWHAG

14-3-3 gamma (also known as YWHAG) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody specifically recognizes gamma isoform of 14-3-3.

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