A2BP1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22647-1-AP

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
mouse brain tissue, human brain tissue

Recommended dilution:
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ataxin 2-binding protein 1

Calculated molecular weight:
395aa,42 kDa

Observed molecular weight:
45-50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
A2BP1

Synonyms
A2BP, A2BP1, ataxin 2 binding protein 1, Fox 1 homolog A, FOX1, HRNBP1, RBFOX1
Background

A2BP1, also named as FOX1 and HRNBP1, contains one RRM (RNA recognition motif) domain. A2BP1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. A2BP1 and ataxin-2 are both localized in the trans-Golgi network. This is a rabbit polyclonal antibody raised against the N terminus of human A2BP1.


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