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  • KD/KO Validated

ADCY8 Polyclonal antibody

ADCY8 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB,ELISA and More (1)

Conjugate

Unconjugated

Cat No : 55065-1-AP

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Synonyms

AC8, ADCY3, ADCY8, adenylate cyclase 8 (brain), Adenylate cyclase type 8, Adenylate cyclase type VIII, Adenylyl cyclase 8, ATP pyrophosphate lyase 8, HBAC1



经过测试的应用

Positive WB detected inNeuro-2a cells, SH-SY5Y cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

55065-1-AP targets ADCY8 in WB, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB,ELISA
Cited ApplicationsWB, IF
Tested Reactivity human, mouse
Cited Reactivityhuman, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name adenylate cyclase 8 (brain)
Synonyms AC8, ADCY3, ADCY8, adenylate cyclase 8 (brain), Adenylate cyclase type 8, Adenylate cyclase type VIII, Adenylyl cyclase 8, ATP pyrophosphate lyase 8, HBAC1
Calculated Molecular Weight 140 kDa
Observed Molecular Weight 140-150 kDa
GenBank Accession NumberNM_001115
Gene Symbol ADCY8
Gene ID (NCBI) 114
RRIDAB_10859258
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP40145
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

ADCY8 Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence. The antibody is specific to ADCY8.

实验方案

Product Specific Protocols
WB protocol for ADCY8 antibody 55065-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIF

Phytochemistry

Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.

Authors - Hong-Ping Long
humanWB

Function (Oxf)

AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels.

Authors - Pulak Kar
humanWB

Nat Commun

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction.

Authors - Xuexin Zhang
  • KD Validated
ratWB,IF

Mol Ther

Inhibition of adenylyl cyclase 8 prevents the upregulation of Orai1 channel which improves cardiac function after myocardial infarction

Authors - Débora Falcón