AKT1/3 Antibody 3 Publications

Mouse Monoclonal| Catalog number: 60203-1-Ig |CloneNo.: 3G5E11

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This Product has been replaced with CatNo. 60203-2-Ig
Our concentration is detected with BSA as standard. A higher concentration will be obtained with IgG as standard.


Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, rat liver tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human breast cancer tissue, human cervical cancer tissue

Positive IF detected in:
MCF-7 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:250-1:1000
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
v-akt murine thymoma viral oncogene homolog 1

Calculated molecular weight:
62 kDa

Observed molecular weight:
62 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AKT1

Synonyms
AKT, AKT1, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
Background

The serine-threonine protein kinase AKT is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT, which then phosphorylates and inactivates components of the apoptotic machinery.


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