ASCL2 Polyclonal antibody

ASCL2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 21368-1-AP

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Synonyms

Achaete scute homolog 2, ASCL2, ASH 2, ASH2, bHLHa45, HASH2, MASH2



经过测试的应用

Positive WB detected inMKN-45 cells, Caco-2 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 21368-1-AP is ASCL2 Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA
Tested Reactivity human
Immunogen ASCL2 fusion protein Ag15839 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name achaete-scute complex homolog 2 (Drosophila)
Synonyms Achaete scute homolog 2, ASCL2, ASH 2, ASH2, bHLHa45, HASH2, MASH2
Calculated Molecular Weight 193 aa, 20 kDa
Observed Molecular Weight20 kDa
GenBank Accession NumberBC057801
Gene Symbol ASCL2
Gene ID (NCBI) 430
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ99929
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Achaete-scute complex homolog 2 (Drosophila), also known as ASCL2, is an imprinted human gene. This gene is involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system, particularly important during implantation of the developing embryo, specifically in placental development and neuronal precursor determination. ASCL2 has been reported involved in tumor progression, being upregulated in colorectal tumors, and involvement in metastasis could be attributed to ASCL2-promoted cellular self-renewal as opposed to cellular differentiation (PMID: 30096149 16568095).

实验方案

Product Specific Protocols
WB protocol for ASCL2 antibody 21368-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols