CD133 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66666-1-Ig |CloneNo.: 2B8A2

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
Human

Positive WB detected in:
HT-29 cells, Caco-2 cells

Recommended dilution:
WB : 1:2000-1:10000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
prominin 1

Calculated molecular weight:
97 kDa

Observed molecular weight:
115 kDa, 80-90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PROM1

Synonyms
AC133, Antigen AC133, CD133, CORD12, MCDR2, MSTP061, PROM1, PROM1 1, PROM1 1,2,3, PROM1 1,2,3,5,7, PROM1 1,6,7, PROM1 2, PROM1 2,3,4,5, prominin 1, Prominin like protein 1, PROML1, RP41, STGD4
Background

CD133, also known as PROM1 (prominin-1) or AC133, belongs to the prominin family. CD133 is a transmembrane glycoprotein with an NH2-terminal extracellular domain, five transmembrane loops and a cytoplasmic tail. The expression of CD133 has been reported in hematopoietic stem cells, endothelial progenitor cells, neuronal and glial stem cells, suggesting the potential role of CD133 as a cell surface marker of adult stem cells. CD133 has also been reported as a marker of cancer stem cells in various human tumors. CD133 is a highly glycosylated protein with an apparent molecular weight of 115-120 kDa. After the treatment of the lysates with glycosidase, CD133 shifted to a protein with an apparent molecular weight of 80-90 kDa (PMID: 23150174; 20068153).


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