Centrin 1 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 12794-1-AP

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse

Positive WB detected in:
HL-60 cells, HL-60 cells, human heart tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
centrin, EF-hand protein, 1

Calculated molecular weight:
172aa,20 kDa

Observed molecular weight:
20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CETN1

Synonyms
Caltractin isoform 2, CEN1, Centrin 1, centrin, EF hand protein, 1, CETN, CETN1
Background

EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Centrin-1 plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. Centrin-1 is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.


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