CK7 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66483-1-Ig |CloneNo.: 2E1G5

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
Human

Positive WB detected in:
A549 cells, A431 cells, T-47D cells, PC-3 cells

Positive IHC detected in:
human lung cancer tissue, human ovary tumor tissue

Recommended dilution:
WB : 1:10000-1:40000
IHC : 1:500-1:2000

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
keratin 7

Calculated molecular weight:
469aa,51 kDa

Observed molecular weight:
51 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT7

Synonyms
CK 7, CK7, Cytokeratin 7, K2C7, K7, keratin 7, KRT7, Sarcolectin, SCL, Type II keratin Kb7
Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT7, also named as cytokeratin 7, is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels, and their neoplasms. KRT7 is marker of epithelial tissues, but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.


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