MTCO2 Antibody 10 Publications

Rabbit Polyclonal| Catalog number: 55070-1-AP

Featured Product KD/KO validated

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse, rat

Positive WB detected in:
HepG2 cells, HeLa cells, HepG2 cells, human placenta tissue, mouse brain tissue, mouse liver tissue, rat liver tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human colon cancer tissue, human breast cancer tissue, human colon cancer tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:5000
IP : 0.5-4.0 ug for IP and 1:500-1:5000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
cytochrome c oxidase II

Calculated molecular weight:
26 kDa

Observed molecular weight:
23-26 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
COX2

Synonyms
COII, COX2, COXII, cytochrome c oxidase II, Cytochrome c oxidase subunit 2, MT CO2, MTCO2
Background

COX2, also named as COII, COXII and MTCO2, belongs to the cytochrome c oxidase subunit 2 family. It is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. Defects in COX2 are a cause of mitochondrial complex IV deficiency (MT-C4D). The antibody is specific to COX2.


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