Caspase 9/p35/p10 Antibody 4 Publications

Mouse Monoclonal| Catalog number: 66169-1-Ig |CloneNo.: 1B7G2

  • Print page
  • Download PDF

Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, Jurkat cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human lymphoma tissue, human lymphoma tissue, human pancreas tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:5000
IP : 0.5-4.0 ug for IP and 1:200-1:2000 for WB
IHC : 1:100-1:400
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
caspase 9, apoptosis-related cysteine peptidase

Calculated molecular weight:
46 kDa

Observed molecular weight:
46 kDa,36 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CASP9

Synonyms
APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, Caspase 9/p35/p10, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6
Background

Caspase 9, apoptosis-related cysteine protease (CASP9,synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Capase 9 is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade.


Back
to top