EXOC5 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 17593-1-AP

Featured Product KD/KO validated

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, human adrenal gland tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human testis tissue, human brain tissue, human testis tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:5000
IP : 0.5-4.0 ug for IP and 1:200-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
exocyst complex component 5

Calculated molecular weight:
708aa,82 kDa

Observed molecular weight:
77 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EXOC5

Synonyms
DKFZp666H126, EXOC5, exocyst complex component 5, HSEC10, PRO1912, SEC10, SEC10L1, SEC10P
Background

EXOC5 (SEC10), a component of the exocyst complex, is a 77-kDa protein with a broad tissue distribution (PubMed: 9119050). The exocyst complex, composed of eight evolutionarily conserved subunits (SEC3, SEC5, SEC6, SEC8, SEC10, SEC15, EXO70, and EXO84), is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The complex is also essential for the biogenesis of epithelial cell surface polarity.


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