- Featured Product
- KD/KO Validated
FBXO17 Polyclonal antibody
FBXO17 Polyclonal Antibody for IF/ICC, IHC, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
IF/ICC, IHC, WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | U-251 cells, mouse heart tissue, HepG2 cells, mouse lung tissue |
| Positive IHC detected in | human heart tissue, human prostate cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF detected in | HepG2 cells, HeLa cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| Immunofluorescence (IF) | IF : 1:20-1:200 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 5 publications below |
| IHC | See 3 publications below |
产品信息
12844-1-AP targets FBXO17 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | IF/ICC, IHC, WB, ELISA |
| Cited Applications | IHC, WB |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Immunogen | FBXO17 fusion protein Ag3867 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | F-box protein 17 |
| Synonyms | F box only protein 17, F box only protein 26, F box protein 17, FBG4, Fbx17, FBX26, FBXO17, FBXO26 |
| Calculated Molecular Weight | 278 aa, 31 kDa |
| Observed Molecular Weight | 29-31 kDa |
| GenBank Accession Number | BC012385 |
| Gene Symbol | FBXO17 |
| Gene ID (NCBI) | 115290 |
| RRID | AB_2877889 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96EF6 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
FBXO17, also named as FBG4, FBX17, FBX26 and FBXO26, is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for FBXO17 antibody 12844-1-AP | Download protocol |
| IHC protocol for FBXO17 antibody 12844-1-AP | Download protocol |
| IF protocol for FBXO17 antibody 12844-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Front Cell Dev Biol A Novel Signature Constructed by RNA-Binding Protein Coding Genes to Improve Overall Survival Prediction of Glioma Patients. | ||
J Biol Chem SCFFBXO17 E3 ligase modulates inflammation by regulating proteasomal degradation of glycogen synthase kinase-3β in lung epithelia. | ||
Carcinogenesis Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma. | ||
J Gene Med Circ_0008717 promotes renal cell carcinoma progression by upregulating FBXO17 via targeting miR-217. | ||
Biosci Biotechnol Biochem F-box protein 17 promotes glioma progression by regulating glycolysis pathway.
| ||
Int J Med Sci FBXO17 Inhibits the Wnt/β-Catenin Pathway and Proliferation of Ishikawa Cells |
