GRP94 Monoclonal antibody, PBS Only (Capture)
GRP94 Monoclonal Antibody for Cytometric bead array, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
Cytometric bead array, ELISA
Conjugate
Unconjugated
CloneNo.
4G7C7
验证数据展示
产品信息
60012-2-PBS targets GRP94 as part of a matched antibody pair:
MP50013-1: 60012-2-PBS capture and 60012-1-PBS detection (validated in Cytometric bead array, Sandwich ELISA)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Applications | Cytometric bead array, ELISA |
| Tested Reactivity | Human |
| Immunogen | GRP94 fusion protein Ag1439 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | heat shock protein 90kDa beta (Grp94), member 1 |
| Synonyms | |
| Calculated Molecular Weight | 96 kDa |
| Observed Molecular Weight | 95 kDa |
| GenBank Accession Number | BC009195 |
| Gene Symbol | HSP90B1 |
| Gene ID (NCBI) | 7184 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P14625 |
| Storage Buffer | 100% PBS pH 7.3 |
| Storage Conditions | Store at -80°C. |
背景介绍
HSP90 proteins are highly conserved molecular chaperones, which normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 (GP96 or GRP94) is an endoplasmic reticulum paralogue of the cytosolic HSP90. As a major ER chaperone to mediate the UPR and a master chaperone for Toll-like receptors (TLRs), HSP90b1 chaperones peptides to MHC class I molecules of dendritic cells and other antigen-presenting cells, as well as facilitating the assembly of immunoglobulin. The protein is also involved in many other bio-processes. This antibody was generated against the N-terminal region of full-length HSP90b1.