• Featured Product
  • KD/KO Validated

HNRNPM Polyclonal antibody

HNRNPM Polyclonal Antibody for IF, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

IF, WB, ELISA

Conjugate

Unconjugated

Cat No : 26897-1-AP

Print datasheet

Synonyms

hnRNP M, HNRNPM, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1



经过测试的应用

Positive WB detected inCOLO 320 cells, MCF-7 cells, HeLa cells, NIH/3T3 cells, Neuro-2a cells
Positive IF detected inHepG2 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26897-1-AP targets HNRNPM in WB, IF, ELISA applications and shows reactivity with human samples.

Tested Applications IF, WB, ELISA
Cited ApplicationsIF, WB
Tested Reactivity human
Cited Reactivityhuman, mouse
Immunogen HNRNPM fusion protein Ag25474 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name heterogeneous nuclear ribonucleoprotein M
Synonyms hnRNP M, HNRNPM, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1
Calculated Molecular Weight 78 kDa
Observed Molecular Weight 73-77 kDa
GenBank Accession NumberBC000138
Gene Symbol HNRNPM
Gene ID (NCBI) 4670
RRIDAB_2880673
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP52272
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

HNRNPM, also named as NAGR1, is a 730 amino acid protein, which localizes in nucleus. HNRNPM as a pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. HNRNPM is Involved in splicing. HNRNPM acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. HNRNPM exists two isoforms with MV 77 kDa and 73 kDa.

实验方案

Product Specific Protocols
WB protocol for HNRNPM antibody 26897-1-APDownload protocol
IF protocol for HNRNPM antibody 26897-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB,IF

Nat Struct Mol Biol

TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.

Authors - Xinxin Zuo
WB

Nat Commun

Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.

Authors - Wen-Juan Li
  • KD Validated
humanWB

Proc Natl Acad Sci U S A

CircURI1 interacts with hnRNPM to inhibit metastasis by modulating alternative splicing in gastric cancer.

Authors - Xiaolin Wang
humanWB

J Exp Clin Cancer Res

PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α.

Authors - Pingfu Hou
humanIF

Nat Commun

Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules

Authors - Tao Wang